Immunosuppressive analogues and derivatives of succinylacetone
US5216005A · kind A · utility
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4References
12Claims
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Key dates
| Filing date | Dec 6, 1990 |
| Grant date | Jun 1, 1993 |
| Priority date | — |
| Expiry date | Dec 6, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/41
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Succinylacetone derived or related medicaments and methods of synthesis of the same are shown wherein the medicaments consists of succinylacetonyl-proline-PEG, succinylacetonyl-NH-PEG, or compounds that have the formula: ##STR1## and that have immunosuppressive activity both in vivo and in vitro based on their activities in cellular immunologic assays and adjuvant induced arthritis in rats, respectively.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.