Selective aortic arch perfusion using perfluorochemical and alpha adrenergic agonist to treat cardiac arrest
US5216032A · kind A · utility
74Cited by
1References
10Claims
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Assignee
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Key dates
| Filing date | Sep 30, 1991 |
| Grant date | Jun 1, 1993 |
| Priority date | — |
| Expiry date | Sep 30, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2202/0476
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of treating a subject in cardiac arrest, comprises blocking the descending aorta of the subject and then perfusing the aortic arch of the subject with a protective solution. The protective solution is one capable of delivering oxygen to the heart of said subject, such as a perfluorochemical blood substitute. Following perfusion, spontaneous circulation is restored. In an improved embodiment of the foregoing, a vasoconstrictor such as epinephrine is administered concurrently with the perfusing step in an amount effective to enhance coronary perfusion with said protective solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.