Oligonucleotide analogs containing sulfur linkages
US5216141A · kind A · utility
689Cited by
5References
3Claims
0Family size
Inventor
Key dates
| Filing date | Jun 6, 1988 |
| Grant date | Jun 1, 1993 |
| Priority date | — |
| Expiry date | Jun 6, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Analogs of DNA containing sulfides, sulfoxides, and sulfones as linking groups between subunits capable of forming bonds with natural oligonucleotides are described. The analogs are lipophilic, stable to chemical degradation under a wide range of conditions and stable to enzymatic degradation in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.