Methods and materials for the preparation of metal labelled antibody solutions
US5217704A · kind A · utility
15Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1991 |
| Grant date | Jun 8, 1993 |
| Priority date | — |
| Expiry date | Dec 27, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a metal ion scavenging procedure and antibody compositions for radioimmunoscintigraphy and cytotoxic radioimmunotherapy having chelator concentrations of greater than about 10.sup.-4 M which are optimized with respect to their metal binding capacity such that highly efficient labelling of the antibody is achieved in a simple one step procedure using readily available sources of radiometal ions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.