Hydroxylation of methyl groups in aromatic heterocycles by microorganisms
US5217884A · kind A · utility
5Cited by
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17Claims
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Key dates
| Filing date | Sep 23, 1991 |
| Grant date | Jun 8, 1993 |
| Priority date | — |
| Expiry date | Sep 23, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/10
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process using microorganisms which contain genes, which form an active xylene monooxygenase, which form no effective, chromosomally or plasmid-coded alcohol hydrogenase, and which are, thus, capable of hydroxylating methyl groups on aromatic 5- or 6-atom heterocycles to the corresponding hydroxymethyl derivatives, for the production of hydroxymethylated 5- or 6-atom heterocycles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.