Monoclonal antibodies recognizing parathyroid hormone-like protein
US5217896A · kind A · utility
24Cited by
0References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 30, 1988 |
| Grant date | Jun 8, 1993 |
| Priority date | — |
| Expiry date | Dec 30, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides a monoclonal antibody which specifically forms a complex with amino acids 1-87 of PTHLP which does not form a complex with amino acids 1-34 of PTHLP, and which forms a complex with the epitope to which any of the monoclonal antibodies produced by the hybridomas 212-10.7, (ATCC Accession No. HB9930), 199-999 (ATCC Accession No. HB9929), 199-278 (ATCC Accession No. HB9931), is directed. This invention further provides methods of detecting PTHLP and of diagnosing and treating humoral hypercalcemia of malignancy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.