Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
US5217992A · kind A · utility
21Cited by
2References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 17, 1990 |
| Grant date | Jun 8, 1993 |
| Priority date | — |
| Expiry date | Sep 17, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. [The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed.] The chemical synthesis of these tocotrienols is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.