Hapten-biotin conjugates and their use

US5219764A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Erasmus Huber · Garching bei München, DE
• Dietmar Zdunek · Tutzing, DE
• Christian Klein · Iffeldorf, DE
• Roland Schenk · Weilheim, DE

Key dates

• Filing date: Apr 10, 1991
• Grant date: Jun 15, 1993
• Expiry date: Apr 10, 2011

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/581
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Hapten-biotin conjugates in which the hapten is linked with biotin via a spacer, which has 26 to 40 atoms in its chain and contains at least 5 heteroatoms, are novel and are suitable, in particular for use in a competitive homogeneous immunoassay in which the agglutination which occurs in the reaction is evaluated by turbidimetric or nephelometric measurements.