Sequential polypeptides endowed with immunological activity
US5219987A · kind A · utility
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3Claims
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Key dates
| Filing date | Aug 2, 1988 |
| Grant date | Jun 15, 1993 |
| Priority date | — |
| Expiry date | Aug 2, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Synthetic polypeptides constituted by at least two consecutive repeating units of (Asn-Asn-Pro) sequence are powerful immunogens in test animals. The formed antibodies recognize both the synthetic polypeptides and the immuno-dominant epitope of the circumsporozoitic protein of Plasmodium falciparum. Said polypeptides, which can be obtained in pure form, are particularly useful for the preparation of antimalarial vaccines and of diagnostic kits for the determination of malarial affections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.