Recombinant antibodies and methods for their production in which surface residues are altered to cysteine residues for attachment of effector or receptor molecules
US5219996A · kind A · utility
148Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 3, 1989 |
| Grant date | Jun 15, 1993 |
| Priority date | — |
| Expiry date | Jul 3, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/867
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides an altered antibody molecule wherein a residue in a surface pocket on the molecule has been changed to a cysteine residue to introduce a thiol group in the surface pocket and a process for its production by recombinant DNA technology.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.