Substituted adamantyl dioxetanes
US5220005A · kind A · utility
32Cited by
1References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 30, 1990 |
| Grant date | Jun 15, 1993 |
| Priority date | — |
| Expiry date | Aug 30, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Dioxetane compounds reactable with an enzyme to release optically detectable eneregy are disclosed. These compounds have the formula: ##STR1## wherein T is a carboxylic acid or methoxy substituted adamantyl group bound to the ring through a spiro bond, Y is phenoxy or napthyloxy and X is methoxy, ethoxy or propoxy. Z is an enzyme cleavable group such that when cleaved by an enzyme, an electron rich moiety is left bound to the dioxetane ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.