Phencyclidine and phencyclidine metabolites assay, tracers, immunogens and antibodies
US5221629A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1990 |
| Grant date | Jun 22, 1993 |
| Priority date | — |
| Expiry date | Jun 14, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/816
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed to a fluorescence polarization assay for phencyclidine and phencyclidine derivatives, to the various components needed for preparing and carrying out such an assay, and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for making them. The tracers and the immunogens are made from substituted phencyclidine compounds. A fluorescein moiety is included in the tracer, while a poly(amino acid) forms a part of the immunogen. The assay is conducted by measuring the degree of polarization retention of plane polarized light that has been passed through a sample containing antiserum and tracer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.