Imidazole derivatives
US5221688A · kind A · utility
9Cited by
3References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 24, 1991 |
| Grant date | Jun 22, 1993 |
| Priority date | — |
| Expiry date | Apr 24, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F3/003
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to salts formed between basic H.sub.2 -receptor antagonists and a complex of zinc with a carboxylic acid selected from tartaric acid, citric acid and alkyl citric acids, and to solvates of such salts, excluding salts in which the basic H.sub.2 -receptor antagonist is ranitidine. Examples of basic H.sub.2 -receptor antagonists are cimetidine, famotidine, nizatidine and roxatidine. The salts are useful in the treatment of gastrointestinal disorders, such as peptic ulcer disease and non-ulcer dyspepsia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.