Bordetella pertussis variants
US5223255A · kind A · utility
1Cited by
1References
6Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 11, 1991 |
| Grant date | Jun 29, 1993 |
| Priority date | — |
| Expiry date | Oct 11, 2011 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/822
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A Bordetella pertussis variant which produces a pertussis toxin mutant protein partially devoid of subunits. When the variants of the present invention are cultured, a pertussis toxin mutant protein partially devoid of subunits, particularly at least subunit S1, can be harvested from the culture. The thus-obtained pertussis toxin mutant protein partially devoid of subunits can be applied to the preparation of a pertussis vaccine by a conventional method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.