Method for detecting organ transplant rejection
US5223396A · kind A · utility
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8Claims
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Key dates
| Filing date | May 3, 1991 |
| Grant date | Jun 29, 1993 |
| Priority date | — |
| Expiry date | May 3, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/245
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for the detection of the presence of inflammation in a patient by measuring the amount of circulating intercellular adhesion molecule (cICAM-1) in a sample of one or more bodily fluids of the patient and then comparing the amount of cICAM-1 in the sample to standards normal for the bodily fluid or fluids assayed. The amount of cICAM-1 can be measured using anti-ICAM-1 antibodies. Higher than normal amounts of cICAM-1 indicate the presence of inflammation. Also contemplated is a method for the detection of organ transplant or tissue graft rejection.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.