Biologically active lipoprotein and its use
US5223481A · kind A · utility
6Cited by
8References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 18, 1989 |
| Grant date | Jun 29, 1993 |
| Priority date | — |
| Expiry date | Oct 18, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A lipoprotein possessing pulmonary surfactant activity comprising an alveolar polypeptide or protein and, covalently bound thereto, one or two fatty acid residue(s); PA1 a pharmaceutical composition comprising such lipoprotein and a phospholipid type of material; and PA1 a method of facilitating respiration in mammals including man, comprising administering an effective amount of such a lipoprotein or pharmaceutical composition to the respiratory tract of a patient subject to respiratory disorder so as to reduce surface tension at the air-liquid interface of the patient's alveoli.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.