Recombinant Alzheimer's protease inhibitory amyloid protein and method of use
US5223482A · kind A · utility
32Cited by
3References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 6, 1989 |
| Grant date | Jun 29, 1993 |
| Priority date | — |
| Expiry date | Jun 6, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/839
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
DNA sequences encoding .beta.-amyloid-related proteins associated with Alzheimer's disease are disclosed. Also provided herein is a DNA sequence encoding a novel protease inhibitor. These sequences are used in producing or constructing recombinant .beta.-amyloid core protein, .beta.-amyloid-related proteins and recombinant or synthetic immunogenic peptides. Antibodies generated against the recombinant proteins or immunogenic peptides derived therefrom can be used for cerebral fluid or serum protein diagnosis of Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.