Technetium-99m labeled somatostatin-derived peptides for imaging
US5225180A · kind A · utility
71Cited by
10References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 10, 1991 |
| Grant date | Jul 6, 1993 |
| Priority date | — |
| Expiry date | Sep 10, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention specifically provides somatostatin, somatostatin derivatives, somatostatin analogues or peptides that bind to the somatostatin receptor and contain at least 2 cysteine residues that form a disulfide or wherein the disulfide is reduced to the sulfhydryl form that are directly labeled with technetium-99m and that can be targeted to specific sites within a mammalian body for imaging.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.