Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them
US5225207A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1991 |
| Grant date | Jul 6, 1993 |
| Priority date | — |
| Expiry date | Oct 15, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F15/0093
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New complexes of general formula (I) in which PA1 R.sub.1 and R.sub.2 together form a saturated or unsaturated polycyclic carbocyclic radical containing 7 to 12 carbon atoms, or a saturated or partially saturated mono-, bi- or tricyclic heterocyclic radical containing 5 to 11 chain members and a hetero-atom chosen from oxygen, sulphur or nitrogen, which latter atom can optionally be substituted by an alkoxycarbonyl radical, and, PA1 X.sub.1 and X.sub.2 represent chlorine atoms or together form PA1 either a radical of structure: ##STR1## in which n is 0 to 2 and R.sub.6 and R.sub.7, which are identical or different, are hydrogen atoms or, when n=1, can be alkyl radicals or form, together with the carbon atom to which they are attached, a cyclobutyl radical, PA1 or a radical of structure: ##STR2## in which n, R.sub.6 and R.sub.7 are defined as above, or their salts where such exist, and their hydrates, their preparation and the pharmaceutical compositions which contain them. ##STR3##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.