Diagnostics for mycobacteria in public health, medical, and veterinary practice
US5225324A · kind A · utility
20Cited by
3References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1992 |
| Grant date | Jul 6, 1993 |
| Priority date | — |
| Expiry date | Apr 14, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a family of DNA insertion sequences (ISMY) of mycobacterial origin and other DNA probes which may be used a probes in assay methods for the identification of mycobacteria and the differentiation between closely related mycobacterial strains and species. In one method the probes are used to distinguish pathogenic M. paratuberculosis from M. avium, which finds an application in the diagnosis of Crohn's disease in humans and Johne's disease in animals. The use of ISMY, and of proteins and peptides encoded by ISMY, in vaccines, pharmaceutical preparations and diagnostic test kits is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.