Patent · US Expired

10-substituted ether derivatives of dihydroartemisinin, process for their preparation and their use as antiprotozoal agents

US5225427A · kind A · utility

10Cited by

5References

7Claims

0Family size

Assignee

Hoechst GmbH · DE

Inventors

Bindumadhavan Venugopalan · Yellandu, IN
Chintamani P. Bapat · Urbana, US
Pravin J. Karnik · Thane, IN
Bansi Lal · Yellandu, IN
Dipak K. Chatterjee · Yellandu, IN
Subramani N. Iver · Yellandu, IN
Richard H. Rupp · Königstein, DE

Key dates

Filing date	Nov 27, 1991
Grant date	Jul 6, 1993
Priority date	—
Expiry date	Nov 27, 2011

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D493/18
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

10-substituted ether derivatives of 3.alpha., 12.alpha.-Epoxy-3,4,5 5a.alpha., 6,7,8,8a.alpha.,9,10,12.beta., 12a-dodecahydro-10-hydroxy-3.beta.,6.alpha.,9.beta.-trimethylpyano-(4,3-j) (1,2) benzodioxepin, also known as Dihydroartemisinin or Dihydroquinghaosu (DHQ), pharmaceutically acceptable salts thereof, processes for their preparation and their use as chemotherapeutics against protozoal infections are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.