Analysis of samples by capillary electrophoretic immunosubtraction
US5228960A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 17, 1992 |
| Grant date | Jul 20, 1993 |
| Priority date | — |
| Expiry date | Jul 17, 2012 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44726
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methodologies for the Capillary Electrophoretic Immunosubtraction ("CEI") of samples. In a preferred embodiment, CEI of a sample comprising constituent parts to be separated comprises the steps of: (1) separating a first aliquot of the sample into constituent parts by capillary electrophoretic techniques, and detecting said parts; (2) admixing a second aliquot of said sample with at least one specific binding partner to a constituent of said sample, said specific binding partner capable of being substantially removed from said aliquot; (3) separating said second aliquot into constituent parts by capillary electrophoretic techniques and detecting said parts; and (4) comparing the separated constituent parts of step (3) with the separated constituent parts of step (1).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.