Method of inhibiting picornavirus disease
US5229111A · kind A · utility
2Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 31, 1991 |
| Grant date | Jul 20, 1993 |
| Priority date | — |
| Expiry date | Jan 31, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/32261
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for inhibiting picornavirus disease in non-murine mammals is disclosed. A vaccine containing a live, recombinant, attenuated picornavirus with a shortened poly(C) tract is administered to the mammal. Preferably, the picornavirus in the vaccine is of the same genus as the disease-causing picornavirus and has a shortened poly(C) tract. The administration of the vaccine causes antibodies effective against the disease-causing picornavirus to be formed in vivo. In one embodiment of the invention, a vaccine containing Mengovirus with a shortened poly(C) tract can be used as a vaccine for both pigs and monkeys.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.