Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
US5229413A · kind A · utility
9Cited by
8References
8Claims
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Key dates
| Filing date | Feb 3, 1992 |
| Grant date | Jul 20, 1993 |
| Priority date | — |
| Expiry date | Feb 3, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/405
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions containing certain indole-2-carboxylate compounds and derivatives are described as being therapeutically effective in treatment of CNS disorders resulting from neurotoxic damage or neurodegenerative diseases, particularly those CNS disorders resulting from ischemic events. Preferred compounds are of the formula ##STR1## wherein each of R.sup.5 and R.sup.6 is independently selected from hydrido, bromo, chloro and fluoro, and wherein each of R.sup.10 and R.sup.12 is independently selected from hydrido and lower alkyl, and pharmaceutically-acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.