Alkylthio alkyl avermectins are active antiparasitic agents
US5229415A · kind A · utility
13Cited by
11References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 24, 1992 |
| Grant date | Jul 20, 1993 |
| Priority date | — |
| Expiry date | Mar 24, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P33/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Avermectin compounds are substituted at the 4", 4' or 13-postion hydroxy group with an alkylthioalkyl group and are optionally substituted at the other reactive positions of the avermectin molecule. The compounds are prepared by reacting protected avermectins, avermectin monosaccharides or avermectin aglycones with dialkylsulfoxides. The compounds are potent antiparasitic agents and compositions for such uses are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.