Substantially pure receptor like TGF-.beta. 1 binding molecules and uses thereof
US5229495A · kind A · utility
48Cited by
0References
5Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 18, 1991 |
| Grant date | Jul 20, 1993 |
| Priority date | — |
| Expiry date | Jun 18, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a family of substantially pure, receptor like TGF-.beta.1 binding glycoproteins. These molecules are characterized by molecular masses of 160 kd, 70-80 kd, and 30-40 kd as determined by SDS-PAGE, and the ability to bind the TGF-.beta.1 molecule. This family of molecules is useful in identifying and/or quantifying TGF-.beta.1 in a sample, as well as inhibiting its effect on cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.