Monoclonal antibodies against human tumor necrosis factor (TNF), and use thereof

US5231024A · kind A · utility

Assignee

• BASF SE

Inventors

• Achim Moeller · Grünstadt, DE
• Franz Emling · Ludwigshafen, DE

Key dates

• Filing date: Sep 8, 1987
• Grant date: Jul 27, 1993
• Expiry date: Sep 8, 2007

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

New hybridoma cell lines which synthesize highly specific monoclonal antibodies (mAb) against human tumor necrosis factor (TNF), monoclonal antibodies against TNF, a process for the preparation of such hybridoma cell lines and antibodies, and the use of the monoclonal antibodies are described.