Azacyclic carboxylic acid derivatives and their preparation and use
US5231106A · kind A · utility
14Cited by
3References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 6, 1991 |
| Grant date | Jul 27, 1993 |
| Priority date | — |
| Expiry date | Dec 6, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel O-alkylated oximes of the general formula I ##STR1## or ##STR2## wherein R.sup.1 and R.sup.2 are optionally substituted aromatic or heteroaromatic rings, R.sup.3 is hydrogen or lower alkyl, R.sup.4 is a nitrogen containing, substituted ring or an amino group carrying a substituted ring, and n and m independently are 0, 1 or 2, are potent inhibitors of GABA reuptake from the synaptic cleft.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.