Compositions containing tris salt of cholesterol hemisuccinate and antifungal
US5231112A · kind A · utility
15Cited by
17References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 23, 1989 |
| Grant date | Jul 27, 1993 |
| Priority date | — |
| Expiry date | Oct 23, 2009 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2984
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions are described for the preparation of bioactive agents entrapped in lipid vesicles the bilayers of which comprise a salt form of an organic acid derivative of a sterol, such as the tris-salt form of a sterol hemisuccinate, and to bompositions comprising a mixture of tris(hydroxymethyl)aminomethane salt of cholesteryl hemisuccinate with either an antifungal compound or a peptide. These compositions have various applications in vivo.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.