Process for producing N-substituted aziridine compound
US5231189A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 20, 1992 |
| Grant date | Jul 27, 1993 |
| Priority date | — |
| Expiry date | Feb 20, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D203/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a novel process for producing an N-substituted aziridine compound by subjecting an N-substituted alkanolamine to a gas-phase catalytic dehydration reaction (the following reaction formula). ##STR1## In the above formula, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each independently one member of selected from a hydrogen atom and alkyl groups of 1-4 carbon atoms, and X is one member selected from alkyl groups of 1-4 carbon atoms, a cyclohexyl group, a phenyl group, a benzyl group, hydroxyalkyl groups of 1-4 carbon atoms and aminoalkyl groups of 1-4 carbon atoms. Preferably, the N-substituted aziridine compound is produced at a high yield by subjecting an N-substituted alkanolamine to a gas-phase catalytic dehydration reaction in the presence of a silicon-containing or phosphorus-containing catalyst under the conditions of reaction pressure=5-250 mmHg, reaction temperature=300.degree.-450.degree. C. and space velocity=50-500 hr.sup.-1 (STP).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.