Patent · US Expired

Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series

US5232917A · kind A · utility

67Cited by
1References
119Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 13, 1991
Grant dateAug 3, 1993
Priority date
Expiry dateAug 13, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J71/001
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Method, compositions, and compounds for modulating brain excitability to alleviate stress, anxiety, insomnia and seizure activity using certain steroid derivatives that act at a newly identified site on the gamma-aminobutyric acid receptor-chloride ionophore (GR) complex.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.