Pyrrolidine derivatives
US5233053A · kind A · utility
26Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 7, 1992 |
| Grant date | Aug 3, 1993 |
| Priority date | — |
| Expiry date | Feb 7, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein R, Y and R.sup.1 are as defined in the specification. These compounds are muscarinic receptor antagonists which are selective for smooth muscle muscarinic sites over cardiac muscarinic sites, and are useful in the treatment of diseases associated with altered motility on tone of smooth muscle, including irritable bowel syndrome, diverticular disease, urinary incontinence, oesophageal achalasia and chronic obstructive airways disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.