Diagnostic assays for genetic mutations associated with bovine leukocyte adhesion deficiency
US5234810A · kind A · utility
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14Claims
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Key dates
| Filing date | Sep 20, 1991 |
| Grant date | Aug 10, 1993 |
| Priority date | — |
| Expiry date | Sep 20, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A point mutation in the CD18 gene responsible for causing bovine leukocyte adhesion deficiency (BLAD) and a silent mutation linked thereto have been identified. Nucleic acid sequences encompassing these mutations serve as bases for testing and identifying cattle alleles attributable to BLAD using any of a variety of diagnostic assays. Suitable nucleic acid probes and primers have also been designed for use in such assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.