Use of sulfonylureas and other potassium channel regulators to treat secretory diarrhea
US5234922A · kind A · utility
21Cited by
1References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 1992 |
| Grant date | Aug 10, 1993 |
| Priority date | — |
| Expiry date | Sep 28, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for the treatment of secretory diarrhea comprised of administering to a patient in need thereof, an effective amount of a CFTR chloride channel blocker or a potassium channel opener are disclosed. The CFTR chloride channel blocker is a sulfonylurea of the group consisting of tolbutamide, glibenclamide, and related analogs. The potassium channel opener is selected from the group consisting of diazoxide, lemakalim, and minoxidil sulfate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.