Production of biologically active, recombinant members of the NGF/BDNF family of neurotrophic proteins
US5235043A · kind A · utility
50Cited by
6References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 9, 1990 |
| Grant date | Aug 10, 1993 |
| Priority date | — |
| Expiry date | Oct 9, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/849
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention describes processes for producing mature human members of the NGF/BDNF family of neurotrophic proteins that are fully biologically active. In addition, the gene encoding human BDNF and processes for obtaining the same are disclosed. A previously-unreported member of the NGF/BDNF family of neurotrophic proteins, NGF-3, has been identified and a portion of the gene encoding for the NGF-3 has been described. Processes for identifying additional previously unreported members of the NGF/BDNF family are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.