Polyethoxylated vitamin E
US5235073A · kind A · utility
12Cited by
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12Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 26, 1992 |
| Grant date | Aug 10, 1993 |
| Priority date | — |
| Expiry date | Mar 26, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/522
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polyethoxylated vitamin E having the formula (I): ##STR1## wherein, R is --CH.sub.2 CH.sub.2).sub.n H, PA1 n is an integer from 2 to 100, inclusive, PA1 A is ##STR2## B is --CH.sub.3 at the 5-, 7- or 8-position, and m is 1, 2 or 3. can be prepared by reacting a vitamin E or an ester thereof with ethylene oxide, using a catalyst under pressure and anhydrous conditions, and shows anti-oxidation and oxidation stability similar to that of vitamin E acetate as well as excellent moisture retention and surfactant activity not shown by vitamin E and vitamin E acetate. Moreover, the compound is highly safe in the living body.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.