Patent · US Expired

Method and apparatus for automated analysis of biological specimens

US5235522A · kind A · utility

66Cited by
13References
27Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 10, 1990
Grant dateAug 10, 1993
Priority date
Expiry dateOct 10, 2010

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06T2207/30024
  • WIPO fieldComputer technology
  • WIPO sectorElectrical engineering

Abstract

An apparatus and method for analyzing the cell objects of a cell sample for the diagnosis and treatment of actual or suspected cancer is disclosed. An image of the cell sample is first digitized and morphological attributes, including area and DNA mass of the cell objects are automatically measured from the digitized image. The measured attributes are compared to ranges of attribute values which are preestablished to select particular cell objects having value in cancer analysis. After the selection of cell objects, the image is displayed to an operator and indicia of selection is displayed with each selected cell object. The operator then reviews the automatically selected cell objects, with the benefit of the measured cell object attribute values and accepts or changes the automatic selection of cell objects. In a preferred embodiment, each selected cell object is assigned to one of six classes and the indicia of selection consists of indicia of the class into which the associated cell object has been placed. The measured DNA mass of identified cell object fragments in tissue section samples may also be increased to represent the DNA mass of the whole cell object from which the f…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.