Derivatives of metalloporphyrins and application thereof for therapeutic purposes and in preparing hybrid molecules
US5236914A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 28, 1990 |
| Grant date | Aug 17, 1993 |
| Priority date | — |
| Expiry date | Nov 28, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F19/005
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Metalloporphyrin derivatives of the formula ##STR1## in which A and B each represents: ##STR2## and Z.sup.+ represents N.sup.+ --R.sub.1 or C--N.sup.+ R.sub.1 R.sub.2 R.sub.3, R.sub.1 being C.sub.1 -C.sub.10 linear or branched aliphatic, and PA1 R.sub.2 and R.sub.3 each being hydrogen or C.sub.1 -C.sub.10 linear or branched aliphatic, PA1 R represents NH.sub.2, OH, COOH or --N(R.sub.1).sub.3 group or a halogen, PA1 n is 0 or an integer from 1 to 10, the corresponding alkylene group being either linear or branched, PA1 M represents Fe or Mn, and PA1 X represents the anion of a pharmaceutically acceptable carboxylic acid, m being an integer from 1 to 5, and PA1 Y represents a bond or a --O--, --CO-- or --CONH-- radical. The compounds have antitumoral and antiviral utility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.