Arylalkylamines, process for preparing them and pharmaceutical compositions containing them
US5236921A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 5, 1991 |
| Grant date | Aug 17, 1993 |
| Priority date | — |
| Expiry date | Sep 5, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to compounds of formula: ##STR1## in which Y represents--either a group Cy--N in which PA1 Cy represents a phenyl, optionally substituted; a C.sub.3 -C.sub.7 cycloalkyl group; a pyrimidinyl group or a pyridyl group; PA0 or a group ##STR2## in which Ar represents a phenyl, optionally substituted, a pyridyl group; a thienyl group; PA1 x is zero or one; PA1 X represents a hydroxyl, a C.sub.1 -C.sub.4 alkoxy; a hydroxyalkyl; a C.sub.1 -C.sub.4 acyloxy; a phenacyloxy; a carboxyl; a C.sub.1 -C.sub.4 carbalkoxy; a cyano; an aminoalkylene; a group --N--(X.sub.1).sub.2 in which the groups X.sub.1 independently represent hydrogen, a C.sub.1 -C.sub.4 alkyl; a group ##STR3## in which Alk represents a C.sub.1 -C.sub.6 alkyl; a group ##STR4## in which the Alk.sub.1 is a C.sub.1 -C.sub.3 alkylene and Alk'.sub.1 is a C.sub.1 -C.sub.3 alkyl; a C.sub.1 -C.sub.4 acyl; a group --S--X.sub.2 in which X.sub.2 represents hydrogen or a C.sub.1 -C.sub.4 alkyl group; or alternatively X forms a double bond with the carbon atom to which it is linked and with the adjacent carbon atom in the heterocycle; PA0 m is 2 or 3; PA0 Ar' represents a phenyl, optionally substituted; a thienyl; a benz…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.