Patent · US Expired

Pharmaceutical compositions, 2-benzothiazolamine derivatives, and their preparation

US5236940A · kind A · utility

31Cited by
1References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 3, 1991
Grant dateAug 17, 1993
Priority date
Expiry dateSep 3, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D277/82
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions are disclosed. They are useful for the treatment of medical conditions associated with the effects of glutamate, comprise as active principle, at least one compound of formula: ##STR1## or a salt thereof, in which either R.sub.1 represents polyfluoroalkoxy, 2,2,2-trifluoroethyl, pentafluoroethyl, tert-butyl, trimethylsilyl or trifluoromethylthio and R.sub.2 and R.sub.3 represent hydrogen, PA1 or R.sub.1 represents polyfluoroalkoxy, R.sub.2 represents hydrogen and R.sub.3 represents alkyl, amino, alkoxy, phenyl, phenylalkyl, dimethylamino or dialkylaminoakylthio, PA1 or R.sub.1 represents polyfluoroalkoxy, R.sub.2 represents amino and R.sub.3 represents hydrogen, with the exception of 6-trifluoromethoxy-2-benzothiazolamine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.