Purified enterotoxin receptor protein
US5237051A · kind A · utility
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Key dates
| Filing date | Dec 6, 1990 |
| Grant date | Aug 17, 1993 |
| Priority date | — |
| Expiry date | Dec 6, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/88
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
RNA has been cloned for the intestinal receptor which recognizes heat stable enterotoxins and has guanylyl cylase activity. The protein sequence has been deduced. The protein has been expressed in cultured cells. Data shows that the protein binds enterotoxin and signals normally through the cyclic GMP second messenger system.
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