Interleukin-2-leukotoxin gene fusions and uses thereof
US5238823A · kind A · utility
14Cited by
12References
14Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 22, 1990 |
| Grant date | Aug 24, 1993 |
| Priority date | — |
| Expiry date | Aug 22, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/75
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
New chimeric proteins, DNA encoding the same, and the use of these proteins in stimulating immunity against respiratory diseases such as pneumonia, including shipping fever pneumonia, are disclosed. The chimeric proteins include at least one epitope of leukotoxin fused to an active fragment of a cytokine. The chimeric proteins can be used in a vaccine composition. Also disclosed are methods of vaccination as well as methods of making the proteins employed in the vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.