Patent · US Expired

Transdermal therapeutic system comprising as active component buprenorphine

US5240711A · kind A · utility

112Cited by

4References

18Claims

0Family size

Assignee

LTS Lohmann Therapie-Systeme GmbH Co. KG · DE

Inventors

Thomas Hille · Neuwied, DE
Lothar Deurer · Koblenz, DE
Hans-Rainer Hoffmann · Neuwied, DE

Key dates

Filing date	Sep 24, 1992
Grant date	Aug 31, 1993
Priority date	—
Expiry date	Sep 24, 2012

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K31/485
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The controlled release of buprenorphine or the pharmaceutically acceptable salts thereof to the skin over a period of time of at least 24 hours is ensured by a transdermal therapeutic system consisting of a backing layer which is impermeable to the active substance, a pressure-sensitive adhesive reservoir layer, and optionally a removable protective layer. Said reservoir layer of said system comprises 20 to 90%-wt polymeric material, 0.1 to 30%-wt softener, 0.1 to 20%-wt buprenorphine base or one of the pharmaceutically acceptable salts thereof, and 0.1 to 30%-wt solvent for the active substance base.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.