Human manganese superoxide dismutase (hMn-SOD)

US5240847A · kind A · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Konrad Heckl · Vaterstetten, DE
• Walter Spevak · Stockerau, AT
• Elinborg Ostermann · Mauerbach, AT
• Andreas Zophel · Neulengbach, AT
• Edeltraud Krystek · Wien, AT
• Ingrid Maurer-Fogy · Wien, AT
• Maria J. Wiche-Castanon · Wien, AT
• Christian Stratowa · Wien, AT
• Rudolf Hauptmann · Ebreichsdorf, AT

Key dates

• Filing date: Mar 11, 1988
• Grant date: Aug 31, 1993
• Expiry date: Mar 11, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/07
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to a method of preparing human Mn-superoxide dismutase (hMn-SOD) by genetic engineering, the DNA sequences which code for this enzyme, suitable vectors which contain these DNA sequences and host cells which can express these DNA sequences, and the enzyme hMn-SOD itself. Suggestions as to the use of this enzyme are also described.