2-(substituted imino)-thiazolidines and process for the preparation thereof
US5240918A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 24, 1992 |
| Grant date | Aug 31, 1993 |
| Priority date | — |
| Expiry date | Mar 24, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new 2-(substituted imino)-thiazolidines, a process for the preparation thereof, pharmaceutical compositions comprising the same, the use of the said 2-(substituted imino)thiazolidines for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The new 2-(substituted imino)-thiazolidine derivatives provided by the present invention correspond to the general formula (I), ##STR1## wherein R.sup.1 and R.sup.2 each represent halogen, nitro, C.sub.1-4 alkoxy or C.sub.1-4 alkyl, which latter may optionally carry one or more halogen substituent(s), PA0 R.sup.3 and R.sup.4 each represent hydrogen or C.sub.1-4 alkyl, PA0 Z denotes oxygen, sulfur or imino, which latter is substituted by a C.sub.1-6 alkyl or a C.sub.1-6 alkenyl group, PA0 R.sup.5 stands for hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkylthio or a group or the formula --NH--R, wherein R represents C.sub.1-6 alkyl, aryl, aralkyl or C.sub.1-6 alkenyl optionally carrying a halogen or a di-(C.sub.1-4 alkyl)-amino substituent; or PA0 Z and R.sup.5 together stand for a trivalent nitrogen atom, with the proviso that if Z denotes a substituted imino gr…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.