Benzopyran class III antiarrhythmic agents
US5240943A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1991 |
| Grant date | Aug 31, 1993 |
| Priority date | — |
| Expiry date | Dec 19, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of the formula ##STR1## or a pharmaceutically acceptable salt thereof; wherein n is 0, 1 or 2; PA0 wherein R is H or lower alkyl of 1 to 6 carbon atoms; PA0 wherein X is selected from the group consisting of hydrogen, methane sulfonamide, nitro, cyano, imidazolyl, alkoxy of 1 to 6 carbon atoms and hydroxy; and PA0 wherein Ar is selected from the group consisting of pyridinyl, tetrahydronaphthalenyl, benzofuranyl, and Ph--CH.dbd.CH-- and phenyl all optionally substituted by methane sulfonamide, nitro, cyano, or imidazolyl with the proviso that when n is 1, Ar is other then phenyl; PA0 pharmaceutical compositions containing these compounds and a method for treating cardiac arrhythmias in mammals by administering the compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.