Solid surface coated with a hydrophilic biopolymer-repellent outer layer and method of making such a surface

US5240994A · kind A · utility

Assignee

• Berol Nobel AB · SE

Inventors

• Carina Brink
• Eva Osterberg · Gothenburg, SE
• Krister Holmberg · Mölndal, SE

Key dates

• Filing date: Sep 13, 1991
• Grant date: Aug 31, 1993
• Expiry date: Sep 13, 2011

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08J2479/00
• WIPO field: Other special machines
• WIPO sector: Mechanical engineering

Abstract

A solid surface having anionic groups capable of reacting with a polyethylene imine substituted at least in part by at least 50% by weight of a hydrophilic nonionic polymer having a molecular weight within the range from about 400 to about 200,000 is provided with a hydrophilic biopolymer-repellent outer surface layer thereof by reacting such a polyethylene imine substituted by nonionic hydrophilic polymer with anionic groups on the solid surface, in an amount sufficient to produce biopolymer-repellent solid surface, and accordingly having low spontaneous adsorption of proteins and other biopolymers through electrostatic attraction and/or hydrophobic interaction.