BR*-diagnostics for monoamine receptors

US5242678A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Bernard Maziere · Gif-sur-Yvette, FR
• Helmut Wachtel · Berlin, DE
• Peter-Andreas Loeschmann · Berlin, DE
• Rainer Dorow · Berlin, DE
• Bernard Acksteiner · Berlin, DE
• Dominique Comar · Paris, FR
• Christian Loch · Paris, FR

Key dates

• Filing date: Jun 26, 1989
• Grant date: Sep 7, 1993
• Expiry date: Jun 26, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2123/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of general Formula I labeled with 7.sup.5 Br, .sup.76 Br, .sup.77 Br, .sup.80m Br or .sup.80 Br isotopes ##STR1## wherein R.sup.6 is a C.sub.1-6 hydrocarbon residue and C.sub.2 C.sub.3, C.sub.9 C.sub.10 is a single or a double bond, as well as their acid addition salts, as diagnostic media to image dopamine.