3-aminopropoxyphenyl derivatives, their preparation and pharmaceutical compositions containing them
US5242943A · kind A · utility
15Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 30, 1991 |
| Grant date | Sep 7, 1993 |
| Priority date | — |
| Expiry date | Jul 30, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D309/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
##STR1## The compounds of Formula I and their physiologically hydrolysable derivatives, in which at least one hydroxy group is in esterified form, and their salts, elicit highly cardioselective beta 1 adrenoceptor blockade, and in most cases cardiospecific blockade, and relevant cardiotonic activity. These compounds can be used as therapeutic agents. One obtains these compounds by 3-amino-2-oxypropylation of the respective substituted phenol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.