Phenylacetamide derivatives and pharmaceutical compositions thereof
US5242944A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 13, 1992 |
| Grant date | Sep 7, 1993 |
| Priority date | — |
| Expiry date | Apr 13, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C237/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides novel phenylacetamide derivatives having the following formula ##STR1## wherein: X is a hydrogen, halogen, hydroxy, nitro, amino, R.sup.1, NR.sup.1 R.sup.2, NHR.sup.1 or OR.sup.1 wherein R.sup.1 and R.sup.2 are an optionally substituted C.sub.1-8 alkyl, cycloalkyl or benzyl group, respectively; Y, which may be the same or different when p is greater than 1, is a hydrogen, halogen, methylenedioxy, hydroxy, trifluoromethyl, R.sup.3 or OR.sup.3 wherein R.sup.3 is an optionally substituted C.sub.1-8 alkyl or benzyl group; PA0 n is an integer from 1 to 6; and PA0 p is an integer from 1 to 5; and pharmaceutically acceptable salts thereof which have powerful analgesic and anti-inflammatory activities. The invention also provides processes for preparing these compounds and pharmaceutical compositions containing them as an active ingredient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.